847 lines
33 KiB
Python
847 lines
33 KiB
Python
"""V2 model classes and training/inference helpers."""
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from __future__ import annotations
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from random import random
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from typing import Optional
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import numpy as np
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import torch
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import torch.nn.functional as F
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from torch import nn
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from torch.utils.data import DataLoader
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from classes.v2.bridges import Bridge
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from classes.v2.towers import ImageTower, MDTower
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# ---------------------------------------------------------------------------
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# Model classes
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# ---------------------------------------------------------------------------
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class SingleEyeHT(nn.Module):
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"""
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ImageTower + MDTower + Bridge, trained on eye-level samples.
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Supports both Classic (eye-level) and Ensemble (patient-level averaging) eval.
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"""
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def __init__(
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self,
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*,
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backbone: str,
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freeze_ratio: float,
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augment: bool,
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clinical_data,
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num_classes: int,
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md_hidden_dim: int = 128,
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fusion_dim: int = 256,
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bridge_mode: str = "fused",
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):
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super().__init__()
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self.img_tower = ImageTower(
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backbone=backbone,
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freeze_ratio=freeze_ratio,
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augment=augment,
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use_se=False,
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)
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self.md_tower = MDTower(
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clinical_data=clinical_data,
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hidden_dim=md_hidden_dim,
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use_se=False,
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)
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self.bridge = Bridge(
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img_dim=self.img_tower.out_dim,
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meta_dim=self.md_tower.out_dim,
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num_classes=num_classes,
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fusion_dim=fusion_dim,
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mode=bridge_mode,
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use_se=False,
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)
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@property
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def transform(self):
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return self.img_tower.transform
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def forward(self, x: torch.Tensor, meta: torch.Tensor) -> torch.Tensor:
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img_feats = None if self.bridge.mode == "metadata_only" else self.img_tower(x)
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md_feats = None if self.bridge.mode == "image_only" else self.md_tower(meta)
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out_f, _, _ = self.bridge(img_feats, md_feats)
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return out_f
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class BilateralHT(nn.Module):
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"""
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Bilateral mode with joint towers:
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- shared eye-level towers encode OD/OS independently
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- joint image and metadata towers combine OD/OS embeddings
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- standard Bridge fuses joint image + joint metadata embeddings
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"""
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def __init__(
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self,
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*,
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backbone: str,
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freeze_ratio: float,
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augment: bool,
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clinical_data,
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num_classes: int,
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md_hidden_dim: int = 128,
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fusion_dim: int = 256,
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):
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super().__init__()
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self.eye_img_tower = ImageTower(
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backbone=backbone,
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freeze_ratio=freeze_ratio,
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augment=augment,
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use_se=False,
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)
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self.eye_md_tower = MDTower(
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clinical_data=clinical_data,
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hidden_dim=md_hidden_dim,
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use_se=False,
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)
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img_dim = self.eye_img_tower.out_dim
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md_dim = self.eye_md_tower.out_dim
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self.joint_img = nn.Sequential(
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nn.Linear(2 * img_dim, fusion_dim),
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nn.LayerNorm(fusion_dim),
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nn.ReLU(),
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nn.Dropout(0.3),
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nn.Linear(fusion_dim, img_dim),
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)
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self.joint_md = nn.Sequential(
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nn.Linear(2 * md_dim, fusion_dim),
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nn.LayerNorm(fusion_dim),
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nn.ReLU(),
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nn.Dropout(0.3),
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nn.Linear(fusion_dim, md_dim),
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)
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self.bridge = Bridge(
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img_dim=img_dim,
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meta_dim=md_dim,
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num_classes=num_classes,
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fusion_dim=fusion_dim,
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mode="fused",
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use_se=False,
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)
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# Auxiliary heads for tower warmup / BCD tower steps.
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self.aux_img = nn.Linear(img_dim, num_classes)
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self.aux_md = nn.Linear(md_dim, num_classes)
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@property
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def transform(self):
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return self.eye_img_tower.transform
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def encode_joint(
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self,
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x_od: torch.Tensor,
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meta_od: torch.Tensor,
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x_os: torch.Tensor,
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meta_os: torch.Tensor,
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) -> tuple[torch.Tensor, torch.Tensor]:
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img_od = self.eye_img_tower(x_od)
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md_od = self.eye_md_tower(meta_od)
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img_os = self.eye_img_tower(x_os)
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md_os = self.eye_md_tower(meta_os)
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joint_img = self.joint_img(torch.cat([img_od, img_os], dim=1))
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joint_md = self.joint_md(torch.cat([md_od, md_os], dim=1))
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return joint_img, joint_md
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def forward(
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self,
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x_od: torch.Tensor,
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meta_od: torch.Tensor,
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x_os: torch.Tensor,
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meta_os: torch.Tensor,
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) -> torch.Tensor:
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joint_img, joint_md = self.encode_joint(x_od, meta_od, x_os, meta_os)
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out_f, _, _ = self.bridge(joint_img, joint_md)
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return out_f
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class FusedEnsembleHT(nn.Module):
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"""
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SingleEyeHT base with a per-eye attention scorer for bilateral fusion.
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The base model is trained eye-level (identical to ensemble mode).
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After base training completes, the base is frozen and only the
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eye_scorer is trained on bilateral (patient-level) samples.
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At inference, eye_scorer is applied independently to each eye's logit
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vector to produce a scalar attention score. Softmax over the two scores
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gives attention weights; the final logit is a weighted sum:
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score_od = eye_scorer(logit_od) # [B, 1]
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score_os = eye_scorer(logit_os) # [B, 1]
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alpha = softmax([score_od, score_os]) # [B, 2], sums to 1
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out = alpha[:,0:1]*logit_od + alpha[:,1:2]*logit_os
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Because eye_scorer is applied to each eye with the same weights, the
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mechanism is permutation-equivariant — there is no left/right positional
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bias. Through training on bilateral labels the scorer learns to give high
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scores to logits that point strongly toward the GC class, creating the
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desired asymmetry: a confidently GC eye dominates the patient prediction
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more than a comparably confident healthy eye would.
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"""
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def __init__(self, base: SingleEyeHT, num_classes: int):
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super().__init__()
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self.base = base
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# Applied independently to each eye's logit → scalar attention score.
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# Learns the GC-direction in logit space from bilateral labels.
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self.eye_scorer = nn.Linear(num_classes, 1, bias=True)
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def forward(
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self,
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x_od: torch.Tensor,
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meta_od: torch.Tensor,
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x_os: torch.Tensor,
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meta_os: torch.Tensor,
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) -> torch.Tensor:
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logit_od = self.base(x_od, meta_od) # [B, C]
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logit_os = self.base(x_os, meta_os) # [B, C]
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scores = torch.cat([self.eye_scorer(logit_od),
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self.eye_scorer(logit_os)], dim=1) # [B, 2]
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alpha = torch.softmax(scores, dim=1) # [B, 2]
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return alpha[:, 0:1] * logit_od + alpha[:, 1:2] * logit_os # [B, C]
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# ---------------------------------------------------------------------------
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# Phase control
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# ---------------------------------------------------------------------------
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def _set_requires_grad(module: nn.Module, enabled: bool) -> None:
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for p in module.parameters():
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p.requires_grad = enabled
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def _set_single_phase(model: SingleEyeHT, phase: str) -> None:
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bridge_mode = model.bridge.mode
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# Ablation modes have no fusion bridge; fused_warmup is meaningless — treat as tower_warmup
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if bridge_mode in ("image_only", "metadata_only") and phase == "fused_warmup":
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phase = "tower_warmup"
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if phase == "md_warmup":
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_set_requires_grad(model.img_tower, False)
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_set_requires_grad(model.md_tower, True)
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_set_requires_grad(model.bridge.classifier_img, False)
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_set_requires_grad(model.bridge.classifier_md, True)
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_set_requires_grad(model.bridge.W_img, False)
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_set_requires_grad(model.bridge.W_md, False)
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_set_requires_grad(model.bridge.classifier_fused, False)
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return
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if phase == "tower_warmup":
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_set_requires_grad(model.img_tower, bridge_mode != "metadata_only")
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_set_requires_grad(model.md_tower, bridge_mode != "image_only")
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_set_requires_grad(model.bridge.classifier_img, bridge_mode != "metadata_only")
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_set_requires_grad(model.bridge.classifier_md, bridge_mode != "image_only")
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_set_requires_grad(model.bridge.W_img, False)
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_set_requires_grad(model.bridge.W_md, False)
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_set_requires_grad(model.bridge.classifier_fused, False)
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return
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if phase == "fused_warmup":
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_set_requires_grad(model.img_tower, False)
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_set_requires_grad(model.md_tower, False)
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_set_requires_grad(model.bridge.classifier_img, False)
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_set_requires_grad(model.bridge.classifier_md, False)
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_set_requires_grad(model.bridge.W_img, True)
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_set_requires_grad(model.bridge.W_md, True)
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_set_requires_grad(model.bridge.classifier_fused, True)
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return
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_set_requires_grad(model, True)
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def _set_bilateral_phase(model: BilateralHT, phase: str) -> None:
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if phase == "tower_warmup":
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_set_requires_grad(model.eye_img_tower, True)
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_set_requires_grad(model.eye_md_tower, True)
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_set_requires_grad(model.joint_img, True)
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_set_requires_grad(model.joint_md, True)
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_set_requires_grad(model.aux_img, True)
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_set_requires_grad(model.aux_md, True)
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_set_requires_grad(model.bridge, False)
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return
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if phase == "fused_warmup":
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_set_requires_grad(model.eye_img_tower, False)
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_set_requires_grad(model.eye_md_tower, False)
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_set_requires_grad(model.joint_img, False)
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_set_requires_grad(model.joint_md, False)
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_set_requires_grad(model.aux_img, False)
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_set_requires_grad(model.aux_md, False)
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_set_requires_grad(model.bridge, True)
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return
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_set_requires_grad(model, True)
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# ---------------------------------------------------------------------------
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# Training helpers
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# ---------------------------------------------------------------------------
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def train_single_epoch(
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model: SingleEyeHT,
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loader: DataLoader,
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opt,
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device: torch.device,
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*,
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phase: str,
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bcd_prob: float = 0.5,
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) -> tuple[float, float]:
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model.train()
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_set_single_phase(model, phase)
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total_loss = total_correct = total_n = 0
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for batch in loader:
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x = batch.get("image_1")
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m = batch.get("matrix_1")
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y = batch.get("label_1")
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if phase == "md_warmup":
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if not torch.is_tensor(m):
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continue
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m = m.to(device)
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y = _to_label_tensor(y, device)
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md_feats = model.md_tower(m)
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logits = model.bridge.classifier_md(md_feats)
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loss = F.cross_entropy(logits, y)
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opt.zero_grad(); loss.backward(); opt.step()
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bs = y.shape[0]
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total_loss += float(loss.item()) * bs
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total_correct += int((logits.argmax(1) == y).sum())
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total_n += bs
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continue
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if not torch.is_tensor(x) or not torch.is_tensor(m):
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continue
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x = x.to(device)
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m = m.to(device)
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y = _to_label_tensor(y, device)
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bridge_mode = model.bridge.mode
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img_feats = None if bridge_mode == "metadata_only" else model.img_tower(x)
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md_feats = None if bridge_mode == "image_only" else model.md_tower(m)
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if phase == "tower_warmup":
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if bridge_mode == "metadata_only":
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logits = model.bridge.classifier_md(md_feats)
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loss = F.cross_entropy(logits, y)
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elif bridge_mode == "image_only":
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logits = model.bridge.classifier_img(img_feats)
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loss = F.cross_entropy(logits, y)
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else:
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logits_i = model.bridge.classifier_img(img_feats)
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logits_m = model.bridge.classifier_md(md_feats)
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loss = 0.5 * (F.cross_entropy(logits_i, y) + F.cross_entropy(logits_m, y))
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logits = 0.5 * (F.softmax(logits_i, dim=1) + F.softmax(logits_m, dim=1))
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elif phase == "fused_warmup":
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logits, _, _ = model.bridge(img_feats, md_feats)
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loss = F.cross_entropy(logits, y)
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else:
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if bridge_mode == "metadata_only":
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logits = model.bridge.classifier_md(md_feats)
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loss = F.cross_entropy(logits, y)
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elif bridge_mode == "image_only":
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logits = model.bridge.classifier_img(img_feats)
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loss = F.cross_entropy(logits, y)
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elif random() < bcd_prob:
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if random() < 0.5:
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logits = model.bridge.classifier_img(img_feats)
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else:
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logits = model.bridge.classifier_md(md_feats)
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loss = F.cross_entropy(logits, y)
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else:
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logits, _, _ = model.bridge(img_feats, md_feats)
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loss = F.cross_entropy(logits, y)
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opt.zero_grad()
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loss.backward()
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opt.step()
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bs = y.shape[0]
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total_loss += float(loss.item()) * bs
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total_correct += int((logits.argmax(1) == y).sum())
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total_n += bs
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return (
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total_loss / total_n if total_n else float("nan"),
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total_correct / total_n if total_n else float("nan"),
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)
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def train_bilateral_epoch(
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model: BilateralHT,
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loader: DataLoader,
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opt,
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device: torch.device,
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*,
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phase: str,
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bcd_prob: float = 0.5,
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) -> tuple[float, float]:
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model.train()
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_set_bilateral_phase(model, phase)
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total_loss = total_correct = total_n = 0
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for batch in loader:
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x1 = batch.get("image_1")
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m1 = batch.get("matrix_1")
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x2 = batch.get("image_2")
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m2 = batch.get("matrix_2")
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y = batch.get("label_1")
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if not (torch.is_tensor(x1) and torch.is_tensor(m1) and torch.is_tensor(x2) and torch.is_tensor(m2)):
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continue
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x1 = x1.to(device); m1 = m1.to(device)
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x2 = x2.to(device); m2 = m2.to(device)
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y = _to_label_tensor(y, device)
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joint_img, joint_md = model.encode_joint(x1, m1, x2, m2)
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if phase == "tower_warmup":
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logits_i = model.aux_img(joint_img)
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logits_m = model.aux_md(joint_md)
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loss = 0.5 * (F.cross_entropy(logits_i, y) + F.cross_entropy(logits_m, y))
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logits = 0.5 * (F.softmax(logits_i, dim=1) + F.softmax(logits_m, dim=1))
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elif phase == "fused_warmup":
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logits, _, _ = model.bridge(joint_img, joint_md)
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loss = F.cross_entropy(logits, y)
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else:
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if random() < bcd_prob:
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if random() < 0.5:
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logits = model.aux_img(joint_img)
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else:
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logits = model.aux_md(joint_md)
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loss = F.cross_entropy(logits, y)
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else:
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logits, _, _ = model.bridge(joint_img, joint_md)
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loss = F.cross_entropy(logits, y)
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opt.zero_grad()
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loss.backward()
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opt.step()
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bs = y.shape[0]
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total_loss += float(loss.item()) * bs
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total_correct += int((logits.argmax(1) == y).sum())
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total_n += bs
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return (
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total_loss / total_n if total_n else float("nan"),
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total_correct / total_n if total_n else float("nan"),
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)
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def train_fusion_epoch(
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model: FusedEnsembleHT,
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loader: DataLoader,
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opt,
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device: torch.device,
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) -> tuple[float, float]:
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"""Train only the fusion head; the base SingleEyeHT is frozen in eval mode."""
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model.base.eval()
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model.eye_scorer.train()
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total_loss = total_correct = total_n = 0
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for batch in loader:
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x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
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x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
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y = batch.get("label_1")
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if not (torch.is_tensor(x1) and torch.is_tensor(m1) and
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torch.is_tensor(x2) and torch.is_tensor(m2)):
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continue
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y_t = _to_label_tensor(y, device)
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out = model(x1.to(device), m1.to(device), x2.to(device), m2.to(device))
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loss = F.cross_entropy(out, y_t)
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opt.zero_grad()
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loss.backward()
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opt.step()
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bs = y_t.shape[0]
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total_loss += float(loss.item()) * bs
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total_correct += int((out.argmax(1) == y_t).sum())
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total_n += bs
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return (
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total_loss / total_n if total_n else float("nan"),
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total_correct / total_n if total_n else float("nan"),
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)
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# ---------------------------------------------------------------------------
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# Inference helpers
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# ---------------------------------------------------------------------------
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def _to_label_tensor(labels, device: torch.device) -> torch.Tensor:
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if torch.is_tensor(labels):
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return labels.to(device=device, dtype=torch.long)
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return torch.as_tensor(labels, dtype=torch.long, device=device)
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def collect_probs_classic(
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model: SingleEyeHT,
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
) -> tuple[np.ndarray, np.ndarray]:
|
|
"""
|
|
Classic eye-level eval using the bilateral val loader.
|
|
OD and OS are treated as independent samples (both contribute to the
|
|
arrays with the same patient label). Returns (y_true [2N], probs [2N, C]).
|
|
"""
|
|
model.eval()
|
|
y_chunks, p_chunks = [], []
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
|
|
x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x1) and torch.is_tensor(m1) and torch.is_tensor(x2) and torch.is_tensor(m2)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
p_od = F.softmax(model(x1.to(device), m1.to(device)), dim=1)
|
|
p_os = F.softmax(model(x2.to(device), m2.to(device)), dim=1)
|
|
y_np = y_t.cpu().numpy()
|
|
y_chunks += [y_np, y_np]
|
|
p_chunks += [p_od.cpu().numpy(), p_os.cpu().numpy()]
|
|
if not y_chunks:
|
|
return np.array([], dtype=np.int64), np.zeros((0, 0), dtype=np.float32)
|
|
return np.concatenate(y_chunks), np.concatenate(p_chunks, axis=0)
|
|
|
|
|
|
def collect_probs_ensemble_pereye(
|
|
model: "SingleEyeHT",
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
*,
|
|
return_ids: bool = False,
|
|
):
|
|
"""
|
|
Per-patient, per-eye probs for all 3 heads from a bilateral loader (ensemble mode).
|
|
|
|
OD corresponds to image_1/matrix_1; OS to image_2/matrix_2.
|
|
Arrays are in patient order (not interleaved at sample level).
|
|
|
|
Returns:
|
|
(y, pf_od, pi_od, pm_od, pf_os, pi_os, pm_os)
|
|
or, when return_ids=True:
|
|
(y, pf_od, pi_od, pm_od, pf_os, pi_os, pm_os, patient_ids)
|
|
|
|
Patient-level averaged ensemble probs can be recovered as:
|
|
p_en = 0.5 * (pf_od + pf_os)
|
|
"""
|
|
model.eval()
|
|
y_chunks: list = []
|
|
pf_od_c, pi_od_c, pm_od_c = [], [], []
|
|
pf_os_c, pi_os_c, pm_os_c = [], [], []
|
|
id_chunks: list[str] = []
|
|
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
|
|
x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x1) and torch.is_tensor(m1) and
|
|
torch.is_tensor(x2) and torch.is_tensor(m2)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
|
|
def _fwd(x, m):
|
|
img_feats = None if model.bridge.mode == "metadata_only" else model.img_tower(x.to(device))
|
|
md_feats = None if model.bridge.mode == "image_only" else model.md_tower(m.to(device))
|
|
out_f, out_i, out_m = model.bridge(img_feats, md_feats)
|
|
pf = F.softmax(out_f, dim=1)
|
|
pi = F.softmax(out_i, dim=1) if out_i is not None else pf
|
|
pm = F.softmax(out_m, dim=1) if out_m is not None else pf
|
|
return pf, pi, pm
|
|
|
|
pf_od, pi_od, pm_od = _fwd(x1, m1)
|
|
pf_os, pi_os, pm_os = _fwd(x2, m2)
|
|
|
|
y_chunks.append(y_t.cpu().numpy())
|
|
pf_od_c.append(pf_od.cpu().numpy()); pi_od_c.append(pi_od.cpu().numpy()); pm_od_c.append(pm_od.cpu().numpy())
|
|
pf_os_c.append(pf_os.cpu().numpy()); pi_os_c.append(pi_os.cpu().numpy()); pm_os_c.append(pm_os.cpu().numpy())
|
|
|
|
if return_ids:
|
|
ids = batch.get("id_1", [""] * len(y_t))
|
|
if torch.is_tensor(ids):
|
|
ids = ids.tolist()
|
|
id_chunks.extend([str(i) for i in ids])
|
|
|
|
if not y_chunks:
|
|
z = np.zeros((0, 0), dtype=np.float32)
|
|
empty_i = np.array([], dtype=np.int64)
|
|
base = (empty_i, z, z, z, z, z, z)
|
|
return base + (np.array([], dtype=object),) if return_ids else base
|
|
|
|
y = np.concatenate(y_chunks)
|
|
pf_od = np.concatenate(pf_od_c, axis=0); pi_od = np.concatenate(pi_od_c, axis=0); pm_od = np.concatenate(pm_od_c, axis=0)
|
|
pf_os = np.concatenate(pf_os_c, axis=0); pi_os = np.concatenate(pi_os_c, axis=0); pm_os = np.concatenate(pm_os_c, axis=0)
|
|
if return_ids:
|
|
return y, pf_od, pi_od, pm_od, pf_os, pi_os, pm_os, np.array(id_chunks, dtype=object)
|
|
return y, pf_od, pi_od, pm_od, pf_os, pi_os, pm_os
|
|
|
|
|
|
def collect_probs_ensemble(
|
|
model: SingleEyeHT,
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
) -> tuple[np.ndarray, np.ndarray]:
|
|
"""
|
|
Patient-level ensemble eval: average OD and OS softmax probabilities.
|
|
Returns (y_true [N], probs [N, C]).
|
|
"""
|
|
model.eval()
|
|
y_chunks, p_chunks = [], []
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
|
|
x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x1) and torch.is_tensor(m1) and torch.is_tensor(x2) and torch.is_tensor(m2)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
p_od = F.softmax(model(x1.to(device), m1.to(device)), dim=1)
|
|
p_os = F.softmax(model(x2.to(device), m2.to(device)), dim=1)
|
|
p = 0.5 * (p_od + p_os)
|
|
y_chunks.append(y_t.cpu().numpy())
|
|
p_chunks.append(p.cpu().numpy())
|
|
if not y_chunks:
|
|
return np.array([], dtype=np.int64), np.zeros((0, 0), dtype=np.float32)
|
|
return np.concatenate(y_chunks), np.concatenate(p_chunks, axis=0)
|
|
|
|
|
|
def collect_probs_bilateral(
|
|
model: BilateralHT,
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
) -> tuple[np.ndarray, np.ndarray]:
|
|
"""Patient-level bilateral eval. Returns (y_true [N], probs [N, C])."""
|
|
model.eval()
|
|
y_chunks, p_chunks = [], []
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
|
|
x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x1) and torch.is_tensor(m1) and torch.is_tensor(x2) and torch.is_tensor(m2)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
p = F.softmax(model(x1.to(device), m1.to(device), x2.to(device), m2.to(device)), dim=1)
|
|
y_chunks.append(y_t.cpu().numpy())
|
|
p_chunks.append(p.cpu().numpy())
|
|
if not y_chunks:
|
|
return np.array([], dtype=np.int64), np.zeros((0, 0), dtype=np.float32)
|
|
return np.concatenate(y_chunks), np.concatenate(p_chunks, axis=0)
|
|
|
|
|
|
def collect_probs_fused(
|
|
model: FusedEnsembleHT,
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
) -> tuple[np.ndarray, np.ndarray]:
|
|
"""Patient-level fused-head eval. Returns (y_true [N], probs [N, C])."""
|
|
model.eval()
|
|
y_chunks, p_chunks = [], []
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
|
|
x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x1) and torch.is_tensor(m1) and
|
|
torch.is_tensor(x2) and torch.is_tensor(m2)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
p = F.softmax(model(x1.to(device), m1.to(device),
|
|
x2.to(device), m2.to(device)), dim=1)
|
|
y_chunks.append(y_t.cpu().numpy())
|
|
p_chunks.append(p.cpu().numpy())
|
|
if not y_chunks:
|
|
return np.array([], dtype=np.int64), np.zeros((0, 0), dtype=np.float32)
|
|
return np.concatenate(y_chunks), np.concatenate(p_chunks, axis=0)
|
|
|
|
|
|
def collect_probs_single_components(
|
|
model: SingleEyeHT,
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
*,
|
|
aggregate_patient: bool,
|
|
return_logits: bool = False,
|
|
):
|
|
"""
|
|
Collect fused/img/md probabilities (and optionally raw logits) for SingleEyeHT.
|
|
- aggregate_patient=False: eye-level (OD/OS as independent samples)
|
|
- aggregate_patient=True : patient-level (average OD/OS per head)
|
|
- return_logits=False: returns (y, probs_f, probs_i, probs_m)
|
|
- return_logits=True: returns (y, probs_f, probs_i, probs_m,
|
|
logits_f, logits_i, logits_m)
|
|
Note: logits are averaged across eyes when aggregate_patient=True,
|
|
which is equivalent to averaging in logit space (before softmax).
|
|
"""
|
|
model.eval()
|
|
y_chunks = []
|
|
pf_chunks, pi_chunks, pm_chunks = [], [], []
|
|
lf_chunks, li_chunks, lm_chunks = [], [], []
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
|
|
x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x1) and torch.is_tensor(m1) and torch.is_tensor(x2) and torch.is_tensor(m2)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
|
|
def _per_eye(x, m):
|
|
img_feats = None if model.bridge.mode == "metadata_only" else model.img_tower(x.to(device))
|
|
md_feats = None if model.bridge.mode == "image_only" else model.md_tower(m.to(device))
|
|
out_f, out_i, out_m = model.bridge(img_feats, md_feats)
|
|
pf = F.softmax(out_f, dim=1)
|
|
pi = F.softmax(out_i, dim=1) if out_i is not None else pf
|
|
pm = F.softmax(out_m, dim=1) if out_m is not None else pf
|
|
lf = out_f
|
|
li = out_i if out_i is not None else out_f
|
|
lm = out_m if out_m is not None else out_f
|
|
return pf, pi, pm, lf, li, lm
|
|
|
|
pf_od, pi_od, pm_od, lf_od, li_od, lm_od = _per_eye(x1, m1)
|
|
pf_os, pi_os, pm_os, lf_os, li_os, lm_os = _per_eye(x2, m2)
|
|
|
|
if aggregate_patient:
|
|
y_chunks.append(y_t.cpu().numpy())
|
|
pf_chunks.append((0.5 * (pf_od + pf_os)).cpu().numpy())
|
|
pi_chunks.append((0.5 * (pi_od + pi_os)).cpu().numpy())
|
|
pm_chunks.append((0.5 * (pm_od + pm_os)).cpu().numpy())
|
|
lf_chunks.append((0.5 * (lf_od + lf_os)).cpu().numpy())
|
|
li_chunks.append((0.5 * (li_od + li_os)).cpu().numpy())
|
|
lm_chunks.append((0.5 * (lm_od + lm_os)).cpu().numpy())
|
|
else:
|
|
y_np = y_t.cpu().numpy()
|
|
y_chunks += [y_np, y_np]
|
|
pf_chunks += [pf_od.cpu().numpy(), pf_os.cpu().numpy()]
|
|
pi_chunks += [pi_od.cpu().numpy(), pi_os.cpu().numpy()]
|
|
pm_chunks += [pm_od.cpu().numpy(), pm_os.cpu().numpy()]
|
|
lf_chunks += [lf_od.cpu().numpy(), lf_os.cpu().numpy()]
|
|
li_chunks += [li_od.cpu().numpy(), li_os.cpu().numpy()]
|
|
lm_chunks += [lm_od.cpu().numpy(), lm_os.cpu().numpy()]
|
|
|
|
if not y_chunks:
|
|
z = np.zeros((0, 0), dtype=np.float32)
|
|
if return_logits:
|
|
return np.array([], dtype=np.int64), z, z, z, z, z, z
|
|
return np.array([], dtype=np.int64), z, z, z
|
|
|
|
y = np.concatenate(y_chunks)
|
|
pf = np.concatenate(pf_chunks, axis=0)
|
|
pi = np.concatenate(pi_chunks, axis=0)
|
|
pm = np.concatenate(pm_chunks, axis=0)
|
|
if return_logits:
|
|
lf = np.concatenate(lf_chunks, axis=0)
|
|
li = np.concatenate(li_chunks, axis=0)
|
|
lm = np.concatenate(lm_chunks, axis=0)
|
|
return y, pf, pi, pm, lf, li, lm
|
|
return y, pf, pi, pm
|
|
|
|
|
|
def collect_probs_eye_level(
|
|
model: "SingleEyeHT",
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
*,
|
|
return_ids: bool = False,
|
|
):
|
|
"""
|
|
Collect fused/img/md probabilities from a single-eye loader (image_1/matrix_1 only).
|
|
Used for eval-mode passes over the training set.
|
|
|
|
Returns (y, probs_f, probs_i, probs_m) or, when return_ids=True,
|
|
(y, probs_f, probs_i, probs_m, sample_ids) where sample_ids is an
|
|
array of strings like "2OD", "4OS".
|
|
"""
|
|
model.eval()
|
|
y_chunks, pf_chunks, pi_chunks, pm_chunks, id_chunks = [], [], [], [], []
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x = batch.get("image_1")
|
|
m = batch.get("matrix_1")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x) and torch.is_tensor(m)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
img_feats = None if model.bridge.mode == "metadata_only" else model.img_tower(x.to(device))
|
|
md_feats = None if model.bridge.mode == "image_only" else model.md_tower(m.to(device))
|
|
out_f, out_i, out_m = model.bridge(img_feats, md_feats)
|
|
pf = F.softmax(out_f, dim=1)
|
|
pi = F.softmax(out_i, dim=1) if out_i is not None else pf
|
|
pm = F.softmax(out_m, dim=1) if out_m is not None else pf
|
|
y_chunks.append(y_t.cpu().numpy())
|
|
pf_chunks.append(pf.cpu().numpy())
|
|
pi_chunks.append(pi.cpu().numpy())
|
|
pm_chunks.append(pm.cpu().numpy())
|
|
if return_ids:
|
|
ids = batch.get("id_1", [""] * len(y_t))
|
|
eyes = batch.get("eye_id_1", [""] * len(y_t))
|
|
# ids/eyes may be tensors (int) or lists of strings
|
|
if torch.is_tensor(ids):
|
|
ids = ids.tolist()
|
|
if torch.is_tensor(eyes):
|
|
eyes = eyes.tolist()
|
|
id_chunks.extend(
|
|
[f"{pid}{eye}" for pid, eye in zip(ids, eyes)]
|
|
)
|
|
|
|
if not y_chunks:
|
|
z = np.zeros((0, 0), dtype=np.float32)
|
|
empty_ids = np.array([], dtype=object)
|
|
if return_ids:
|
|
return np.array([], dtype=np.int64), z, z, z, empty_ids
|
|
return np.array([], dtype=np.int64), z, z, z
|
|
|
|
y = np.concatenate(y_chunks)
|
|
pf = np.concatenate(pf_chunks, axis=0)
|
|
pi = np.concatenate(pi_chunks, axis=0)
|
|
pm = np.concatenate(pm_chunks, axis=0)
|
|
if return_ids:
|
|
return y, pf, pi, pm, np.array(id_chunks, dtype=object)
|
|
return y, pf, pi, pm
|
|
|
|
|
|
def collect_probs_bilateral_components(
|
|
model: BilateralHT,
|
|
loader: DataLoader,
|
|
device: torch.device,
|
|
) -> tuple[np.ndarray, np.ndarray, np.ndarray, np.ndarray]:
|
|
"""Collect fused/img/md probabilities for bilateral joint-tower model."""
|
|
model.eval()
|
|
y_chunks = []
|
|
pf_chunks, pi_chunks, pm_chunks = [], [], []
|
|
with torch.no_grad():
|
|
for batch in loader:
|
|
x1 = batch.get("image_1"); m1 = batch.get("matrix_1")
|
|
x2 = batch.get("image_2"); m2 = batch.get("matrix_2")
|
|
y = batch.get("label_1")
|
|
if not (torch.is_tensor(x1) and torch.is_tensor(m1) and torch.is_tensor(x2) and torch.is_tensor(m2)):
|
|
continue
|
|
y_t = _to_label_tensor(y, device)
|
|
joint_img, joint_md = model.encode_joint(
|
|
x1.to(device), m1.to(device), x2.to(device), m2.to(device)
|
|
)
|
|
out_f, _, _ = model.bridge(joint_img, joint_md)
|
|
out_i = model.aux_img(joint_img)
|
|
out_m = model.aux_md(joint_md)
|
|
y_chunks.append(y_t.cpu().numpy())
|
|
pf_chunks.append(F.softmax(out_f, dim=1).cpu().numpy())
|
|
pi_chunks.append(F.softmax(out_i, dim=1).cpu().numpy())
|
|
pm_chunks.append(F.softmax(out_m, dim=1).cpu().numpy())
|
|
if not y_chunks:
|
|
z = np.zeros((0, 0), dtype=np.float32)
|
|
return np.array([], dtype=np.int64), z, z, z
|
|
return (
|
|
np.concatenate(y_chunks),
|
|
np.concatenate(pf_chunks, axis=0),
|
|
np.concatenate(pi_chunks, axis=0),
|
|
np.concatenate(pm_chunks, axis=0),
|
|
)
|
|
|
|
|
|
# ---------------------------------------------------------------------------
|
|
# V2ModeComparisonOps — thin class wrapper kept for external import compat
|
|
# ---------------------------------------------------------------------------
|
|
|
|
class V2ModeComparisonOps:
|
|
"""Namespace wrapper kept for backward-compatibility imports."""
|
|
|
|
_set_requires_grad = staticmethod(_set_requires_grad)
|
|
_set_single_phase = staticmethod(_set_single_phase)
|
|
_set_bilateral_phase = staticmethod(_set_bilateral_phase)
|
|
train_single_epoch = staticmethod(train_single_epoch)
|
|
train_bilateral_epoch = staticmethod(train_bilateral_epoch)
|
|
collect_probs_classic = staticmethod(collect_probs_classic)
|
|
collect_probs_ensemble = staticmethod(collect_probs_ensemble)
|
|
collect_probs_bilateral = staticmethod(collect_probs_bilateral)
|
|
|
|
@staticmethod
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def _to_label_tensor(labels, device: torch.device) -> torch.Tensor:
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return _to_label_tensor(labels, device)
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