rpotter6298
169 lines
7.7 KiB
Python
169 lines
7.7 KiB
Python
#!/usr/bin/env python3
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"""Validate PCA-50 feature K-means on the same Task06 test patients as siamese."""
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import os, sys, json, argparse
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import numpy as np
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import matplotlib; matplotlib.use("Agg")
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import matplotlib.pyplot as plt
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from PIL import Image as PILImage
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os.environ["OMP_NUM_THREADS"] = "1"
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os.environ["OPENBLAS_NUM_THREADS"] = "1"
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os.environ["MKL_NUM_THREADS"] = "1"
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sys.path.insert(0, os.path.dirname(os.path.dirname(os.path.dirname(os.path.abspath(__file__)))))
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from classes import PatientIdentifier, FeatureExtractor
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from sklearn.metrics import adjusted_rand_score, normalized_mutual_info_score
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ROOT = os.path.dirname(os.path.dirname(os.path.dirname(os.path.abspath(__file__))))
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PNG_DIR = os.path.join(ROOT, "features", "task06_pngs", "test")
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RESULTS_DIR = os.path.join(ROOT, "results", "clustering_validation")
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PLOTS_DIR = os.path.join(ROOT, "plots")
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SEED = 42
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MODELS = ["VGG16", "DenseNet121", "EfficientNetB1", "MobileNetV2", "ResNet50"]
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def cluster_purity_stats(y_true, y_pred):
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purities = []; overall_correct = 0
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for c in np.unique(y_pred):
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mask = y_pred == c
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_, counts = np.unique(y_true[mask], return_counts=True)
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purities.append(counts.max() / mask.sum())
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overall_correct += counts.max()
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purities = np.array(purities)
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return {"overall": float(overall_correct / len(y_true)),
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"median": float(np.median(purities)), "mean": float(np.mean(purities)),
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"frac_gt_70": float((purities > 0.7).mean()),
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"frac_gt_90": float((purities > 0.9).mean())}
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def patient_capture_stats(y_true, y_pred):
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captures = []
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for p in np.unique(y_true):
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mask = y_true == p
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p_clusters = y_pred[mask]
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_, counts = np.unique(p_clusters, return_counts=True)
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captures.append(counts.max() / mask.sum())
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captures = np.array(captures)
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return {"median": float(np.median(captures)), "mean": float(np.mean(captures)),
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"frac_gt_50": float((captures > 0.5).mean())}
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def plot_assignment_matrix(y_true, y_pred, out_path, title):
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true_patients = sorted(np.unique(y_true))
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pred_clusters = sorted(np.unique(y_pred))
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matrix = np.zeros((len(true_patients), len(pred_clusters)))
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for i, p in enumerate(true_patients):
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for j, c in enumerate(pred_clusters):
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matrix[i, j] = ((y_true == p) & (y_pred == c)).sum()
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matrix_norm = matrix / (matrix.sum(axis=1, keepdims=True) + 1e-8)
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fig, ax = plt.subplots(figsize=(max(14, len(pred_clusters)*0.22), max(10, len(true_patients)*0.18)))
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cmap = plt.cm.YlOrRd.copy()
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cmap.set_under('white')
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ax.imshow(matrix_norm, aspect="auto", cmap=cmap, vmin=1e-6, vmax=1)
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ax.set_xticks(range(len(pred_clusters)))
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ax.set_xticklabels([f"c{c}" for c in pred_clusters], fontsize=6, rotation=90)
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ax.set_yticks(range(len(true_patients)))
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ax.set_yticklabels(true_patients, fontsize=7)
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ax.set_xlabel("Predicted cluster"); ax.set_ylabel("True patient")
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ax.set_title(title, fontsize=11)
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plt.colorbar(ax.images[0], ax=ax, label="Fraction of patient's slices")
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plt.tight_layout()
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os.makedirs(os.path.dirname(out_path), exist_ok=True)
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plt.savefig(out_path, dpi=150); plt.close()
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print(f" Heatmap → {out_path}")
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def main():
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ap = argparse.ArgumentParser()
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ap.add_argument("--model", default="VGG16", choices=MODELS)
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ap.add_argument("--all-models", action="store_true")
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ap.add_argument("--tag", default="")
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ap.add_argument("--full", action="store_true",
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help="Run on full NIfTI dataset (63 patients, not just test).")
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args = ap.parse_args()
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tag = f"_{args.tag}" if args.tag else ""
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os.makedirs(RESULTS_DIR, exist_ok=True); os.makedirs(PLOTS_DIR, exist_ok=True)
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if args.full:
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tag = (tag or "") + "_full"
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from classes import NiftiSliceDataset
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VOL = os.path.join(os.path.dirname(ROOT), "Task06_Lung", "imagesTr")
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ds = NiftiSliceDataset(VOL, random_slices=False, seed=SEED, rotate_deg=90)
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ds.load_all_slices(stride=1)
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test_slices = ds.slices_rgb
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test_pids = ds.patient_labels
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test_fnames = ds.filenames
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y_true_map = {f: pid for f, pid in zip(test_fnames, test_pids)}
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k = ds.n_patients
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y_true = np.array([y_true_map[f] for f in test_fnames])
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print(f" FULL dataset: {len(test_fnames)} slices, {k} patients")
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else:
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manifest_path = os.path.join(PNG_DIR, "manifest.json")
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if not os.path.exists(manifest_path):
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print(f"Test PNGs not found at {PNG_DIR}. Run train_siamese.py first.")
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sys.exit(1)
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with open(manifest_path) as f: png = json.load(f)
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test_paths = png["paths"]
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test_pids = np.array(png["patient_ids"])
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test_fnames = [p.split("/")[-1].replace(".png", "") for p in test_paths]
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y_true_map = {f: pid for f, pid in zip(test_fnames, test_pids)}
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k = len(np.unique(test_pids))
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y_true = np.array([y_true_map[f] for f in test_fnames])
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test_slices = [PILImage.open(p).convert("L") for p in test_paths]
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print(f" {len(test_fnames)} slices, {k} patients (same test set as siamese)")
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models_to_run = MODELS if args.all_models else [args.model]
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for model_name in models_to_run:
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print(f"\n{'─'*50}")
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print(f"Model: {model_name}")
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print(f"{'─'*50}")
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print(f" Extracting features ...", flush=True)
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ext = FeatureExtractor(model_name=model_name)
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X, _, _ = ext.extract_from_images(test_slices)
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print(f" Clustering PCA-50 into k={k} ...", flush=True)
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ident = PatientIdentifier(patient_estimates={"lung": k}, random_state=SEED)
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groups = ident.identify_from_features(X, np.full(len(X), "lung"))
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y_pred = np.array([str(g) for g in groups])
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purity = cluster_purity_stats(y_true, y_pred)
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capture = patient_capture_stats(y_true, y_pred)
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ari = adjusted_rand_score(y_true, y_pred)
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nmi = normalized_mutual_info_score(y_true, y_pred)
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print(f"\n RESULTS — PCA-50 K-means ({model_name})")
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print(f" {'─'*45}")
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print(f" ARI: {ari:.4f}")
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print(f" NMI: {nmi:.4f}")
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print(f" Overall purity: {purity['overall']:.3f} ({purity['overall']*100:.1f}%)")
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print(f" Mean capture: {capture['mean']:.3f} ({capture['mean']*100:.1f}%)")
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results = {"method": f"pca50_{model_name}", "model": model_name,
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"n_patients": int(k), "n_slices": len(test_fnames),
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"ARI": ari, "NMI": nmi,
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"cluster_purity": purity, "patient_capture": capture}
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out_json = os.path.join(RESULTS_DIR, f"validate_pca50_{model_name}{tag}.json")
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with open(out_json, "w") as f: json.dump(results, f, indent=2)
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print(f" Metrics → {out_json}")
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plot_assignment_matrix(y_true, y_pred,
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os.path.join(PLOTS_DIR, "clustering_validation", "pca50",
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f"assignment_matrix_{model_name}{tag}.png"),
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f"PCA-50 K-means {model_name} (ARI={ari:.3f}, purity={purity['overall']:.1%}, capture mean={capture['mean']:.1%})")
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# Summary table if all models
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if args.all_models:
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print(f"\n{'='*60}")
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print("SUMMARY — All models")
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print(f"{'='*60}")
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print(f"{'Model':<18s} {'ARI':>7s} {'Purity':>8s} {'Capture':>8s}")
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print("-" * 43)
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for model_name in MODELS:
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j = os.path.join(RESULTS_DIR, f"validate_pca50_{model_name}{tag}.json")
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if os.path.exists(j):
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with open(j) as f: d = json.load(f)
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print(f"{model_name:<18s} {d['ARI']:>7.3f} {d['cluster_purity']['overall']:>7.1%} {d['patient_capture']['mean']:>7.1%}")
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print("DONE")
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if __name__ == "__main__": main()
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